FITC标记的氢离子转运ATP合成酶6G抗体
产品名称： FITC标记的氢离子转运ATP合成酶6G抗体
英文名称： Anti-ATP6V1G2/FITC
产品编号： HZ-10930R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ATP6V1G2/FITC Conjugated antibody
FITC标记的氢离子转运ATP合成酶6G抗体
| 英文名称 | Anti-ATP6V1G2/FITC |
| 中文名称 | FITC标记的氢离子转运ATP合成酶6G抗体 |
| 别 名 | ATP6G; ATP6G2; ATPase H+ transporting lysosomal (vacuolar proton pump) subunit G; ATPase H+ transporting lysosomal 13kDa V1 subunit G2; H(+) transporting two sector ATPase subunit G2; NG 38; NG38; V ATPase 13 kDa subunit 2; V ATPase G subunit 2; V ATPase subunit G 2; Vacuolar ATP synthase subunit G 2; Vacuolar proton pump G subunit 2; Vacuolar proton pump subunit G 2; VMA 10; VMA10. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 14kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ATP6V1G2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene. [provided by RefSeq, Feb 2011] Function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Subunit: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d). Subcellular Location: Melanosome. Note=Highly enriched in late-stage melanosomes. Tissue Specificity: Brain. Similarity: Belongs to the V-ATPase G subunit family. Database links: Entrez Gene: 534 Human Omim: 606853 Human SwissProt: O95670 Human Unigene: 249227 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码空泡ATPase(V-ATPase)的组分，V-ATPase是介导真核细胞胞内腔酸化的多亚基酶。V-ATPase依赖的酸化作用对于蛋白质分选、酶原激活、受体介导的内吞作用以及突触囊泡质子梯度的产生等细胞内过程是必需的。V-ATP酶由胞浆V1结构域和跨膜V0结构域组成。V1结构域由三个A和三个B亚基组成，两个G亚基加上C、D、E、F和H亚基。V1结构域包含ATP催化位点。V0结构域由五个不同的亚基组成：a、c、c’、c’、和d。许多V1和V0亚基蛋白的其他同工型由多个基因或选择性剪接的转录变体编码。该编码蛋白是三个V1结构域G亚单位蛋白之一。该基因具有ATP6G和ATP6G2的前基因符号。另外，已经描述了编码不同亚型的剪接转录变体。该基因和下游DEAD(Asp-Glu-Ala-Asp)盒多肽39B(DDX39B)基因之间也存在读出转录。[ RefSeq，FEB 2011 ]提供