FITC标记的甲基转移酶样蛋白3抗体-抗体-抗体-生物在线
FITC标记的甲基转移酶样蛋白3抗体

FITC标记的甲基转移酶样蛋白3抗体

商家询价

产品名称: FITC标记的甲基转移酶样蛋白3抗体

英文名称: Anti-METTL3/FITC

产品编号: HZ-17609R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-METTL3/FITC Conjugated antibody

FITC标记的甲基转移酶样蛋白3抗体

 

英文名称 Anti-METTL3/FITC
中文名称 FITC标记的甲基转移酶样蛋白3抗体
别    名 IME4; Methyltransferase like protein 3; Methyltransferase-like protein 3; Methyltransferase like 3; METTL3; MT-A70; MTA70; MTA70_HUMAN; N6 adenosine methyltransferase 70 kDa subunit; N6-adenosine-methyltransferase 70 kDa subunit.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human METTL3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]

Function:
N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation.

Subcellular Location:
Nucleus speckle. Colocalizes with speckles in interphase nuclei. Suggesting that it may be associated with nuclear pre-mRNA splicing components.

Tissue Specificity:
Widely expressed at low level. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the MT-A70-like family.

Database links:

Entrez Gene: 56339 Human

Entrez Gene: 56335 Mouse

Entrez Gene: 361035 Rat

Omim: 612472 Human

SwissProt: Q86U44 Human

SwissProt: Q8C3P7 Mouse

Unigene: 168799 Human

Unigene: 271759 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

该基因编码MT-A的70 kDa亚基,其是N6腺苷甲基转移酶的一部分。该酶参与真核mRNA内腺苷残基的转录后甲基化,形成N6-甲基腺苷。[ RefSeq,JUL 2008 ]