分子量：Calculated MW: 24kDa
Observed MW: 27kDa

细胞定位：Cytoplasm

稀释方法：WB 1:500 - 1:2000
IF 1:10 - 1:100

总结：The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.