FITC标记的类表皮生长因子域7抗体
产品名称： FITC标记的类表皮生长因子域7抗体
英文名称： Anti-EGFL7/FITC
产品编号： HZ-1755R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-EGFL7/FITC Conjugated antibod
FITC标记的类表皮生长因子域7抗体
| 英文名称 | Anti-EGFL7/FITC |
| 中文名称 | FITC标记的类表皮生长因子域7抗体 |
| 别 名 | EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGFL 7; Epidermal growth factor like domain protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple epidermal growth factor like domain protein 7; NEU1 protein; NOTCH4 like protein; RP11 251M1.2; Vascular endothelial statin; VE statin; ZNEU 1; ZNEU1; EGFL7_HUMAN; EGFL7_MOUSE. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 生长因子和激素 转录调节因子 激酶和磷酸酶 内皮细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse EGFL7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro. Function: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro. Subcellular Location: Secreted (By similarity). Tissue Specificity: Expressed specifically by endothelial cells of the highly vascularized organs heart, lung and kidney. Similarity: Contains 2 EGF-like domains. Contains 1 EMI domain. Database links: Entrez Gene: 51162 Human Entrez Gene: 353156 Mouse Omim: 608582 Human SwissProt: Q9UHF1 Human Unigene: 91481 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
EGFL7（EGF-样结构域含蛋白7）在体内调节血管生成。在新生血管形成过程中，内皮细胞群（ECS）在称为芽的单位中迁移。EGFL7调节每个芽内ECS的适当空间组织并影响它们的集体运动。在体外，它抑制血小板衍生生长因子（PDGF）-BB诱导的平滑肌细胞迁移，并促进内皮细胞与底物的粘附。